Where do you draw the line?

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I grew up in a slightly disunctional family and prefer to say yes instead of say no and face the consequences. I cannot stand confrontation and hat ebeing yelled at. So, when people ask me to help them out or do a favor I say, SURE. I have now reached the point where my plate is too full and I get stressed just figuring out my schedule. When do you draw the line. Do I suddenly have to become a b*tch to everyone or just start with anyone who asks me from now on?