not working: front panel usb; sd/mmc/sm/ms-pro; cf/microdriver and two rear usb

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The front panel digital media manager - usb port, sd/mmc/sm/ms-pro, cf/microdrive, two rear usb ports and the ethernet port stopped working. I have an emachines w3050. Any Ideas on where to start the troubleshooting???? I have the motherboard manual now, but still don't have a clue where to start. any help at all will be appreciated. thanks