My daughter is leaving for college on East Coast. Any advice?

What city is she moving to?

Make sure, where ever your child is going, that all recommended vaccinations are up to date. Students in dorms are prone to a certain type of bacterial meningitis, and if not required it is recommended that they get vaccinated. Your daughter should enjoy being there, and take advantage of all cultural opportunities. It is different from West Coast, and I live right in the middle, but have visited both. It is wise not to go to a different state with the presupposition that where you come from is superior, or inferior, for that matter. She should just enjoy the differences.

Besides the difference in weather, I'm not sure what the difference would be. As long as your daughter is responsible yet willing to explore and have fun while she is in school there should be nothing to worry about. She will have a great experience regardless of where she goes.