How Parents tell whether or not kids are experimenting with drugs and alcohol?

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I know kids face difficult decisions. Being involve in your child's life is extremely important in ensuring the don't end up taking the wrong path. Research from the partnership for a drug-free America shows that kids who learn consistently from their parents about the risk of drugs and alcohol are up to 50% less likely to use than those who don't. What clues can you share to identify whether kids may be experimenting with drugs and alcohol?