When do you leave?

Once you realise that you are not compatible and "you feel worthless and unappreciated". Then you must leave. your continuous stay may possibly lproduce an ugly result.

I guess for me it would depend on a few things for the "how" part (like are there kids involved, who's name is on the lease, what my money situation is like etc)...At what point would I leave though? As soon as it started to affect me mentally and emotionally on a daily basis or even a regular basis..especially if I'd brought it up in conversation and my partner had no intention of changing OR he/she changed for a short bit to keep me quiet but then it went right back to the way it was....That just tells me that he/she really doesnt give a crap and I'm not really that important to him/her....

I would suggest seeing other people because time is definitely being wasted when you could be focusing more time on yourself instead of with someone that it's not even working out with.