How active and alert we are after 45 years ?

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The general belief is that only youth are energetic and capable of bringing new changes to life. Does it mean that the wisdom you gain out of experience does not worth a dime ?! What about a person, though middle aged, having a lot of experience and longing to have a business started of his own. He would know the twists of life in real time situation. He is capable of handling such a situtation of his own. But how many people who are middle aged are active.