Can all the drugs (legal) that we take really be good for us?

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Okay, so here's the deal. I am a diabetic, have heart disease, neuropathy in my feet, peripheral artery disease, and COPD, along with some other less-serious health problems. I take about 10 different prescription medications per day. And, I know there those out there who take even more than that. My question is do you think that it could possibly be safe to take so many different drugs every day? Please let me know your thoughts on this subject. Thank you all.