My Depressed Friend

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I have a friend who is depressed. She told my the other day that she is going to quit leading our local girl scout troop. This surprises me because even during her hospital stay, she expressed strongly that she wanted to keep acting in that capacity and we; her family, the other co-leaders and myself, did whatever we could to help her with that. She cut down drastically on her other outside activities and is now shutting out her family. Her husband seems like a loving and suportive person, he works and helps with cooking and housework. She homeschools and is behind with it, which worries me. Anyway, I cannot understand what has triggered her episode. It seemed like things were going great during the summer until she started cancelling meetings and not meeting her committments. She used to take great pride in her house and garden, but I can see a marked difference in these as she has let things slide. She is now on medication, but it seems like she is getting worse. I don't know how to help her.