Your Best Friend, and how you choose them?

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I've had this best friend for many years, and we both always considered ourselves to be just like sisters. Well, the past 2 years or more, our iteractions have come to be soo far and in between and on her part. I first started calling and leaving messages for her either at work or at home. Then emailed many times. I had no problems with the email going through until a couple of months ago. They started coming back. I came across her cell phone number around that same time, so I called and low and behold she answered. She was on her way to the dentist so she could'nt talk at the time, although she told me she was just mentioning to a friend of ours that same day that she was going to call me. What a coincedence we both agreed about that. Well, she told me she would call me later that night and gave me her new email address. Well, she did'nt call back that night at all. The next day I sent an email asking how she made out at the dentist and to call me that night when she got a chance for I missed her call from the night before. Well, no word, hide, or hair from her since then. My sister is right, she seems to only call when she has problems and nothing going right. I decided I was done trying to get ahold of her. Now it's her turn or I guess another friendship lost. It took me awhile to open up to let another friend in, I've been burnt too many times from so called friends, that I've decided my friends are pretty much my family. There are a few friends/acquaintences, but that's about it. As for someone to really talk to, I'm sticking with my sisters. The qualities I look for in a friend, is someone who is real all the way through, true and honest. Not a part time friend, not only calling upon you when there's problems. Open, honest, sincere, and there for me as I'm there for you. How about you? What makes your best friend your best friend? Does this person, in real life, a true friend to you? What qualities do you look for?