what is life's greatest pain?

the greatest pain in this life is when someone you believe (like your best friend) cheating with your girl behind you. And when you caught them, he never say Sorry and he just leave you behind and carry your girl. What about you?

The greatest pain in life is witnessing the girl you love best into other guy's hand and you can not do anything to prevent it.

I think the greatest pain would be when you lose yourself. It would be very hard to live life being manipulated and exploited by others and have no meaning to one's life. Self loathing and self denial sounds horrible and such misery might project itself in bad ways leading to more damage. It is great to be yourself and have confidence and belief in yourself and in what you do.

greatest pain is being lied to.... Dying is a fact of life. Having someone ignore you or abandoned you is their loss. Being lied to is just - well wrong and total pos me.

losing a loved one of course even though others have said it is definitely one of the greatest pains you will ever feel in your life. but i would like to also say that another great pain one would definitely feel would be the loss of love and I don't mean if that person happens to die i mean when love just stops being there or you are cheated on and you have invested so much emotion into that relationship that it feels that all of you is put into that relationship so when that ends. it feels like you have lost yourself completely. so for me it would be losing a love in my life.