I do not know how i can help my best friend, i can t make her to talk !!

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It is very difficult, i love her a lot,i really care about her, is my model for life, is a remarkable woman, is an absolutely amazing sincerity is beautiful, smart, proper, is an excellent mother, and rarely i saw a friend like her, but I can not understand, I can not do something to make her to talk with me about what she feel, what she want, why she is now in a deep depression.She say that she is ok, does not want to admit she has a problem, something happens to her, that needs to remove out all the pain of her soul. All the time when I had a problem she was there, listen to me, support me, caressing me.I know her for many years, she was like a sister for me when I needed a shoulder to cry, she was there. Although she is very strong, always has been stronger than those around her, and she was single parents, she have a business that is not a dependent by anyone, now I feel it is weak, i sense that she lost trust in people, it seems that just does not trust me .. In the last year she lost someone very important in her life, and it seems that this has affected a lot, and was betrayed by someone waiting too. Furthermore I do not know, do not let me go beyond the wall on which she build around her Step by step, she cut all relations with people around her, don t want talk, don t want comunicate, she only work, and work again. How i can help her? I need advices, i need somebody tell me what i must to do in this situation, she learn me how i must ask a question when i come in this site, so...now i will ask; what i can do for my friend?