Why is the number 666 associated with the devil?

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It's unclear why the specific number 666 is the number of the beast. According to Dial-the-Truth Ministries, the number 6 is the number of man because in the Bible, God created man on the sixth day. Elsewhere in the Bible (Matthew 16:23), Satan is described as being "man-centered" (as opposed to God-centered). Thus the devil's number would be a twist on man's number. This is just one theory, and the number 666 has generated plenty of debate.