Depression, what are the causes? and does it have a cure?

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These are the questions I keep asking myself whenever I read stories both online and on newspapers about kids that took their life as a result of depression. All the time. I could be laughing and having a great time with my friends, which I often am because my friends are great, and yet in the back of my mind I feel more alone than ever and I just want to curl up into fetal position and cry. But I never can. I can’t go home and cry and then feel better, because it’s not like there is something to cry about, or really anything to be sad about. And it isn’t really sadness. It is complete solitude. It’s when my brain tells me that I am alone, that I can’t be loved, that no one really wants me around, and worst of all that no one will understand me. That's just how I feel whenever I am depressed. That is worst of all because at the place I am in my life, no matter what I have been through in the past, or what my depression tries to make me believe I know that I can be loved, that I’m not alone and that I am wanted. And I know that because of the hard work I have done to get to that place in my life, and because of some of the amazing people in my life who make sure that I know that they are there for me, that they love me, and that they want to spend time with me. I have being in and out of depression several times and I learned to take control of myself whenever I am depressed. So guys, have you ever being depressed before? What did you do? How are you able to overcome it. Please do share so other might learn one or two things from it.