does the devil really wear prada? fact or fiction?

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Is there such a woman so evil that you almost killed her for that? A woman so twisted or a retard that gets in your nerves. A woman who doesn't even care for her own well being or even her own family. Because I don't believe such woman exist in this world. A woman can be as twisted a she can be if she is psychotic or something really bad happened to her that caused her to be like that. Do you know anybody or heard anybody's story encounteringthese women?