How do you choose the right decision for the future when there are so many?

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I'm currently in college and I can't make up my mind. Sometimes I don't want to be in college sometimes I want to. Sometimes I only think about staying because my parents want me to. Sometimes I don't want to major in communications I want to recieve an associate degree in small business/entrepreneurship but I'm to afraid because after I finish I have to start a business what if the business fails. Sometimes I want to leave college and try to make my career without a degree through work experience and real life challenges. There's always this hope in my gut that maybe it'll work then reality sets in and I think I have better chances if I stay in college. How do you decide what to do when you have so many things to choose from? How do you make a decision you won't regret or that won't work out badly? Has anyone ever been in this situation? How did it turn out for you?