How much work is too much???

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How much wotk is too much? I think that depending on your position and your home life that there should be a limit on over working. For instance, the people i work with work till 2 am sometimes and are here in the morning to start all over again. I feel kinda bad because I know they need help; but I have 3 children at home that need me to be home. So give me your opinions, How much work is too much?