What is the biggest mistake of your life?

I cant think what is the biggest of my life because I did not do something wrong about my life, as of now, all that I am doing is right.

Same here. The biggest mistake I've done so far was to trust with all my heart. Without hesitation. I mean, I should have done it in moderation. Trusting is not bad but giving your trust to someone who's not deserving is another thing. I trusted a few wrong people and they hurt me in return. Not that I am blaming them or something because if you think of it, nobody told me to trust them anyways. It's my voluntary action. So, I am the only one to blame. Bottom line is, we all need to learn to choose who to give trust to. Save it for the person who really deserves it.

i m still continuing with that .i always trust anyone to be true. i loved everyone. i cant hide my emotions to anybody. my face is just a mirror of my heart. which i think is very negative in this meterialistic world.

Not saying NO. I said yes when I should have just stood up for myself and said NO. Agreeing to things that I did not want to do is probably what I would classify as the many mistakes of my life. I think this ties in with your comment about trusting too much aswell.